A segfault and NaN driven series of disconnected ideas, analyses and just plain silly posts about computational biochemistry, synthetic biology and microbiology.
Showing posts with label biochemistry. Show all posts
Showing posts with label biochemistry. Show all posts
Sunday, 31 December 2023
A possible BioB bipass route
Nearly a decade ago there was something bugging me and I believe I have figured it out —although it's pointless now. Namely, is another way of making biotin possible without using BioB, biotin synthase, an incredibly slow multistep radical SAM enzyme.
Sunday, 15 December 2019
What-if: Biosynthesis of deazaguanine
7-deazaguanine is an analogue of guanine that has a carbon instead of a nitrogen. This molecule that is not made in nature, but many substituted versions, namely queine, archaeosine nucleobase and their precursors. These are made via a different route. However, it would be very feasible to make via straightforward enzymology.
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